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Skip to main content home help publications browse by subject resources about us login enter e-mail address enter password remember me not registered? Forgotten password? Institutional login > home > hematology > hematology > european journal of haematology > vol 37 issue 4 > abstract journal tools get new content alerts get rss feed save to my profile get sample copy recommend to your librarian journal menu journal home find issues current issue all issues find articles early view accepted articles most accessed get access subscribe / renew for contributors onlineopen author guidelines submit an article about this journal news overview editorial board permissions advertise contact special features bloodmed wiley job network pipobroman therapy of essential thrombocythemia m. G. Mazzucconi m. D. *, m. Francesconi, a. Chistolini, e. Falcione, a. Ferrari, m. C. Tirindelli, f. Mandelli article first published online: 20 jan 2012 doi: 10. 1111/j. 1600-0609. 1986. Tb02317. X © munksgaard 1986 issue european journal of haematology volume 37, issue 4, pages 306–309, october 1986 additional information how to cite mazzucconi, m. G. , francesconi, m. , chistolini, a. , falcione, e. , ferrari, a. , tirindelli, m. C. And mandelli, f. (1986), pipobroman therapy of essential thrombocythemia. European journal of haematology, 37: 306–309. Doi: 10. 1111/j. 1600-0609. 1986. Tb02317. X author information institute of hematology, department of human biopathology, university la sapienza, rome, italy * institute of hematology via benevento 6 00161 rome italy publication history issue published online: 20 jan 2012 article first published online: 20 jan 2012 accepted for publication may 12, 1986 search search scope all content publication titles in this journal in this issue search string advanced > saved searches > search by citation volume: issue: page: article tools get pdf (225k) save to my profile e-mail link to this article export citation for this article get citation alerts request permissions abstract references cited by get pdf (225k) keywords: essential thrombocythemia; pipobroman; secondary neoplasms we report our results with pipobroman (pb) therapy in patients with essential thrombocythemia (et). cheap viagra online cheap viagra online buy generic viagra buy viagra buy viagra without prescriptions cheap generic viagra viagra online canada pharmacy viagra without a doctor prescription generic viagra cheap viagra online 21 consecutive untreated patients were treated with pb from 1975 to 1984. Pb was given at a dose of 1 mg/kg/d until platelet count dropped below 600 × 109/l. In 18 patients (86%) a hematological remission was obtained. Median duration of induction phase was 49 d. In all cases a maintenance regimen was required at a dose ranging from 0. 2 mg/kg/d to 0. 5 mg/kg/d, according to platelet number. Follow‐up of responder patients ranged from 6 to 108 months (median 17 months). Treatment was well tolerated and we observed only a very moderate and transient hematological toxicity. No patient had relapsed or d.

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